Product Specifications
- Molecular Formula
- C101H152N28O22S2
- Molecular Weight
- 2174.6g/mol
- Sequence
- Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Purity
- ≥99% (HPLC verified)
- Form
- Lyophilized powder
- Appearance
- White to off-white powder
- Solubility
- Soluble in water, bacteriostatic water
- Storage
- -20°C (lyophilized), 2-8°C (reconstituted)
About MOTS-C
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a unique mitochondrial-derived peptide that functions as a systemic signaling molecule. In research settings, it is primarily studied for its role in metabolic homeostasis and its ability to regulate the AICAR-AMPK pathway. MOTS-c is unique because it is encoded in the mitochondrial DNA rather than the nuclear DNA. Research indicates that it targets skeletal muscle to enhance glucose metabolism and increase fatty acid oxidation. It is widely utilized in studies involving aging, obesity, and physical performance, as it appears to mimic many of the physiological benefits of exercise at a cellular level. This high-purity lyophilized reagent provides a consistent standard for exploring mitochondrial-to-nuclear communication.
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